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Talking to Your Doctor About XOLAIR

If you think you may have allergic asthma, seeking out an allergist or a pulmonologist who can diagnose and treat your condition is an important step. Next, you want to be sure you're prepared to get the most out of your office visit. Here is a good place to start. Throughout this website you’ve probably seen questions that you can add to My Q’s. My Q’s is a collection tool that helps you build your Doctor Discussion Guide. All of the My Q’s questions on the site are included below, along with several others.

XOLAIR is not a substitute for the medicines you are already taking. Do not change or stop taking any of your other asthma medicines unless your doctor tells you to do so.

Build Your Doctor Discussion Guide

Click on the questions you’d like to include in your Doctor Discussion Guide and they will be added to My Q’s. The questions you’ve already selected are indicated below. You can edit your selections for My Q’s at any time.

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Questions about allergic asthma

  • Could my asthma be allergic asthma?
  • What is IgE?
  • Can I get an IgE test?
  • Why do you think it would be good for me to see an allergist or a pulmonologist?
  • Why is my allergic asthma still uncontrolled?
  • How do I know if I have moderate to severe allergic asthma?
  • I avoid certain things that trigger my asthma symptoms, such as _________________. Is this normal?
  • What else can I do to avoid triggers I’m allergic to?

Questions about XOLAIR

  • Would XOLAIR be right for me?
  • Can you explain the risk and potential side effects of XOLAIR to me?
  • How does XOLAIR work?
  • How often would I need to go for XOLAIR injections?
  • Where would I have to go for XOLAIR injections?
  • How long does each XOLAIR injection visit take?
  • How long does it take for XOLAIR to start working?
  • Why is XOLAIR an injection?
  • What happens if I miss an injection?

Questions about allergic asthma treatment

  • Are there other medications that block IgE?
  • If my asthma is uncontrolled, what else can I do?
  • If you don’t think XOLAIR is right for me, what else can I do to manage my moderate to severe allergic asthma?

Questions about what to expect on XOLAIR

  • Is it common to have an allergic reaction to XOLAIR?
  • I’ve had allergy shots in the past. Are XOLAIR injections given in a different way?
  • Can I take XOLAIR with the other medications I’m currently taking?

Questions about paying for XOLAIR

  • Will my insurance cover XOLAIR?
  • Am I eligible for the XOLAIR Co-pay Card?
  • How long will it take to get insurance approval for XOLAIR?
  • How do I get started with XOLAIR Access Solutions?
  • I understand there are programs that may help me pay for XOLAIR. How does that work?

Selected Questions

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      What is XOLAIR?

      XOLAIR® (omalizumab) for subcutaneous use is an injectable prescription medicine used to treat adults and children 12 years of age and older with moderate to severe persistent asthma whose asthma symptoms are not controlled by asthma medicines called inhaled corticosteroids. A skin or blood test is performed to see if you have allergies to year-round allergens.

      XOLAIR is not used to treat other allergic conditions, acute bronchospasm or status asthmaticus.


      What is the most important information I should know about XOLAIR?

      A severe allergic reaction called anaphylaxis can happen when you receive XOLAIR. The reaction can occur after the first dose, or after many doses. It may also occur right after a XOLAIR injection or days later. Anaphylaxis is a life-threatening condition and can lead to death. Go to the nearest emergency room right away if you have any of these symptoms of an allergic reaction:

      • wheezing, shortness of breath, cough, chest tightness, or trouble breathing
      • low blood pressure, dizziness, fainting, rapid or weak heartbeat, anxiety, or feeling of "impending doom"
      • flushing, itching, hives, or feeling warm
      • swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing

      Your healthcare provider will monitor you closely for symptoms of an allergic reaction while you are receiving XOLAIR and for a period of time after your injection. Your healthcare provider should talk to you about getting medical treatment if you have symptoms of an allergic reaction after leaving the healthcare provider's office or treatment center.

      Do not receive XOLAIR if you are allergic to omalizumab or any of the ingredients in XOLAIR.

      Before receiving XOLAIR, tell your healthcare provider about all of your medical conditions, including if you:

      • have any other allergies (such as food allergy or seasonal allergies)
      • have sudden breathing problems (bronchospasm)
      • have ever had a severe allergic reaction called anaphylaxis
      • have or have had a parasitic infection
      • have or have had cancer
      • are pregnant or plan to become pregnant. It is not known if XOLAIR may harm your unborn baby.
      • if you become pregnant while taking XOLAIR, talk to your healthcare provider about registering with the XOLAIR Pregnancy Registry. You can get more information and register by calling 1-866-4XOLAIR (1-866-496-5247) or visit
      • are breastfeeding or plan to breastfeed. It is not known if XOLAIR passes into your breast milk.

      Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, or herbal supplements.

      How should I receive Xolair?

      • Xolair should be given by your healthcare provider, in a healthcare setting.
      • Xolair is given in 1 or more injections under the skin (subcutaneous), 1 time every 2 or 4 weeks.
      • In asthma patients, a blood test for a substance called IgE must be performed prior to starting Xolair to determine the appropriate dose and dosing frequency. Do not decrease or stop taking any of your other asthma medicine unless your healthcare providers tell you to.
      • You may not see improvement in your symptoms right away after Xolair treatment.

      What are the possible side effects of XOLAIR? XOLAIR may cause serious side effects, including:

      • See, "What is the most important information I should know about XOLAIR" regarding the risk of anaphylaxis.
      • Cancer. People who receive treatment with XOLAIR may have a higher chance for getting certain types of cancer.
      • Fever, muscle aches, and rash. Some people who take XOLAIR get these symptoms 1 to 5 days after receiving a XOLAIR injection. If you have any of these symptoms, tell your healthcare provider.
      • Parasitic infection. Some people who are at a high risk for parasite (worm) infections, get a parasite infection after receiving XOLAIR. Your healthcare provider can test your stool to check if you have a parasite infection.
      • Some people who receive XOLAIR have had chest pain, heart attack, blood clots in the lungs or legs, or temporary symptoms of weakness on one side of the body, slurred speech, or altered vision. It is not known whether this is caused by Xolair.

      The most common side effects of XOLAIR:

      • Pain especially in your arms and legs, dizziness, feeling tired, skin rash, bone fractures, and pain or discomfort of your ears.

      These are not all the possible side effects of XOLAIR. Call your doctor for medical advice about side effects.

      You may report side effects to the FDA at (800) FDA-1088 or You may also report side effects to Genentech at (888) 835-2555 or Novartis Pharmaceuticals Corporation at 888-669-6682.

      Please see full Prescribing Information, including Medication Guide, for additional important safety information.

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