TERMS & CONDITIONS

The XOLAIR® Specialist Locator (the "Locator") is compiled and published by Genentech, Inc. and Novartis Pharmaceuticals Corporation (referred to as "the Companies") as a reference source of demographic and professional information on certain individual physicians in the United States. The only permitted uses of the Locator are for: (i) the personal convenience of individual members of the general public to facilitate quick access to information about physicians with whom they may be consulting regarding medical services; and (ii) individual physicians or their staff to add, update, or view their personal listings or those of colleagues for professional purposes such as patient referrals. Neither the Locator nor any of its data, listings, or other constituent elements may be downloaded, republished, resold, duplicated, used, or reused, in whole or in part, for any purpose other than the personal uses permitted above.

You cannot use the Locator to verify credentials of any particular Specialist. The database of physician information that is used to compile and publish the Locator does not contain sufficient information with which to verify physician credentials. Inclusion in this database is based on a physician's response to a communication to all allergists and pulmonologists in the American Academy of Allergy, Asthma and Immunology list. This database is compiled for informational purposes only.

You should conduct your own inquiry concerning the credentials of any physician before consulting that physician regarding medical services. Your selection of a specialist is your sole responsibility and is a decision that should be undertaken with care. For example, you may consider checking credentials with the appropriate medical boards. In addition, you can obtain names of other specialists (not listed within the Locator) by contacting a medical society.

The Companies disclaim any responsibility to update or otherwise maintain the information contained in the Locator. Furthermore, because the Companies: (i) compile such information from independent sources over whom the Companies have no control, and (ii) may experience reporting and processing errors or delays with respect to the information obtained through this website including, without limitation, the implied warranties of merchantability and fitness for any particular purpose. The material included in this website is for informational purposes only.

Inclusion of a specialist is not and does not imply referral, endorsement, or recommendation by the Companies, nor does the omission of any individual indicate disapproval by the Companies.

The Companies shall not be liable to you or others for any decisions made or action taken by you or others in reliance on the information obtained from this website.

Who is XOLAIR for?

XOLAIR^® (omalizumab) for subcutaneous use is an injectable, prescription medicine for patients 12 years of age and older. It is for patients with moderate to severe persistent allergic asthma caused by year-round allergens in the air. A skin or blood test is done to see if you have allergic asthma. XOLAIR is for patients who are not controlled by asthma medicines called inhaled steroids.

XOLAIR helps reduce the number of asthma attacks in people with allergic asthma who still have asthma symptoms even though they are taking inhaled steroids.

Important Limitations of Use

• XOLAIR has not been proven to work in other allergic conditions.
• XOLAIR is not a rescue medicine and should not be used to treat sudden asthma attacks.
• XOLAIR should not be used in children under 12 years of age.

IMPORTANT SAFETY INFORMATION

XOLAIR should always be injected in a doctor's office. You should read the Medication Guide before starting XOLAIR treatment and before each and every treatment.

A severe allergic reaction called anaphylaxis has happened in some patients after they received XOLAIR. Anaphylaxis is a life-threatening condition and can lead to death so get emergency medical treatment right away if signs or symptoms of anaphylaxis occur after receiving XOLAIR.

• wheezing, shortness of breath, cough, chest tightness, or trouble breathing
• low blood pressure, dizziness, fainting, rapid or weak heartbeat, anxiety, or feeling of "impending doom"
• flushing, itching, hives, or feeling warm
• swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing

Anaphylaxis from XOLAIR can happen:

• right after receiving a XOLAIR injection or hours later
• after any XOLAIR injection. Anaphylaxis has occurred after the first XOLAIR injection or after many XOLAIR injections.

Your healthcare provider should watch you for some time in the office for signs or symptoms of anaphylaxis after injecting XOLAIR. If you have signs or symptoms of anaphylaxis, tell your healthcare provider right away.

You should not receive XOLAIR if you have ever had an allergic reaction to a XOLAIR injection. Do not use XOLAIR if you are allergic to any of its ingredients.

In clinical studies, a variety of cancer types, including breast, skin, prostate, and parotid (a type of salivary gland), were reported in more patients who received XOLAIR than in patients who did not receive XOLAIR.

XOLAIR is not a rescue medicine and should not be used to treat sudden asthma attacks.

XOLAIR is not a substitute for the medicines you are already taking. Do not change or stop taking any of your other asthma medicines unless your doctor tells you to do so.

Some patients on XOLAIR may have an abnormal increase in eosinophils (a type of white blood cell) in the blood or tissues, sometimes causing an inflammation of blood vessels, which can lead to rash, worsening of respiratory symptoms, heart trouble, and/or nerve pain and weakness.

Joint inflammation or pain, rash, fever, and swollen lymph nodes have been seen in some patients taking XOLAIR after the first or subsequent injections. Talk to your doctor if you've experienced any of these signs and symptoms.

The most commonly seen side effects occurring more frequently in patients receiving XOLAIR than in patients who received placebo (an injection with no active medicine) were joint pain, pain (general), leg pain, tiredness (fatigue), dizziness, fracture, arm pain, itching, inflammation of the skin, and earache.

In asthma studies, the most common side effects in patients, who either needed to stop XOLAIR or needed medical attention, were injection site reaction, viral infections, upper respiratory tract infection, sinusitis, headache, and sore throat. These side effects were seen at similar rates in XOLAIR-treated patients as in patients that did not receive XOLAIR.

There are other possible side effects with XOLAIR. Talk to your doctor for more information and if you have any questions about your treatment.

XOLAIR has not been studied in pregnant women. Pregnant women exposed to XOLAIR are encouraged to enroll in the XOLAIR Pregnancy Exposure Registry. You can get more information by calling 1-866-4XOLAIR (1-866-496-5247) or by speaking with your doctor.

Please see accompanying full Prescribing Information, including Medication Guide, for additional important safety information.

Who is XOLAIR for?

XOLAIR^® (omalizumab) for subcutaneous use is an injectable, prescription medicine for patients 12 years of age and older. It is for patients with moderate to severe persistent allergic asthma caused by year-round allergens in the air. A skin or blood test is done to see if you have allergic asthma. XOLAIR is for patients who are not controlled by asthma medicines called inhaled steroids.

XOLAIR helps reduce the number of asthma attacks in people with allergic asthma who still have asthma symptoms even though they are taking inhaled steroids.

Important Limitations of Use

• XOLAIR has not been proven to work in other allergic conditions.
• XOLAIR is not a rescue medicine and should not be used to treat sudden asthma attacks.
• XOLAIR should not be used in children under 12 years of age.

IMPORTANT SAFETY INFORMATION

XOLAIR should always be injected in a doctor's office. You should read the Medication Guide before starting XOLAIR treatment and before each and every treatment.

A severe allergic reaction called anaphylaxis has happened in some patients after they received XOLAIR. Anaphylaxis is a life-threatening condition and can lead to death so get emergency medical treatment right away if signs or symptoms of anaphylaxis occur after receiving XOLAIR.

• wheezing, shortness of breath, cough, chest tightness, or trouble breathing
• low blood pressure, dizziness, fainting, rapid or weak heartbeat, anxiety, or feeling of "impending doom"
• flushing, itching, hives, or feeling warm
• swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing

Anaphylaxis from XOLAIR can happen:

• right after receiving a XOLAIR injection or hours later
• after any XOLAIR injection. Anaphylaxis has occurred after the first XOLAIR injection or after many XOLAIR injections.

Your healthcare provider should watch you for some time in the office for signs or symptoms of anaphylaxis after injecting XOLAIR. If you have signs or symptoms of anaphylaxis, tell your healthcare provider right away.

You should not receive XOLAIR if you have ever had an allergic reaction to a XOLAIR injection. Do not use XOLAIR if you are allergic to any of its ingredients.

In clinical studies, a variety of cancer types, including breast, skin, prostate, and parotid (a type of salivary gland), were reported in more patients who received XOLAIR than in patients who did not receive XOLAIR.

XOLAIR is not a rescue medicine and should not be used to treat sudden asthma attacks.

XOLAIR is not a substitute for the medicines you are already taking. Do not change or stop taking any of your other asthma medicines unless your doctor tells you to do so.

Some patients on XOLAIR may have an abnormal increase in eosinophils (a type of white blood cell) in the blood or tissues, sometimes causing an inflammation of blood vessels, which can lead to rash, worsening of respiratory symptoms, heart trouble, and/or nerve pain and weakness.

Joint inflammation or pain, rash, fever, and swollen lymph nodes have been seen in some patients taking XOLAIR after the first or subsequent injections. Talk to your doctor if you've experienced any of these signs and symptoms.

The most commonly seen side effects occurring more frequently in patients receiving XOLAIR than in patients who received placebo (an injection with no active medicine) were joint pain, pain (general), leg pain, tiredness (fatigue), dizziness, fracture, arm pain, itching, inflammation of the skin, and earache.

In asthma studies, the most common side effects in patients, who either needed to stop XOLAIR or needed medical attention, were injection site reaction, viral infections, upper respiratory tract infection, sinusitis, headache, and sore throat. These side effects were seen at similar rates in XOLAIR-treated patients as in patients that did not receive XOLAIR.

There are other possible side effects with XOLAIR. Talk to your doctor for more information and if you have any questions about your treatment.

XOLAIR has not been studied in pregnant women. Pregnant women exposed to XOLAIR are encouraged to enroll in the XOLAIR Pregnancy Exposure Registry. You can get more information by calling 1-866-4XOLAIR (1-866-496-5247) or by speaking with your doctor.

Please see accompanying full Prescribing Information, including Medication Guide, for additional important safety information.

TERMS & CONDITIONS

The XOLAIR® Specialist Locator (the "Locator") is compiled and published by Genentech, Inc. and Novartis Pharmaceuticals Corporation (referred to as "the Companies") as a reference source of demographic and professional information on certain individual physicians in the United States. The only permitted uses of the Locator are for: (i) the personal convenience of individual members of the general public to facilitate quick access to information about physicians with whom they may be consulting regarding medical services; and (ii) individual physicians or their staff to add, update, or view their personal listings or those of colleagues for professional purposes such as patient referrals. Neither the Locator nor any of its data, listings, or other constituent elements may be downloaded, republished, resold, duplicated, used, or reused, in whole or in part, for any purpose other than the personal uses permitted above.

You cannot use the Locator to verify credentials of any particular Specialist. The database of physician information that is used to compile and publish the Locator does not contain sufficient information with which to verify physician credentials. Inclusion in this database is based on a physician's response to a communication to all allergists and pulmonologists in the American Academy of Allergy, Asthma and Immunology list. This database is compiled for informational purposes only.

You should conduct your own inquiry concerning the credentials of any physician before consulting that physician regarding medical services. Your selection of a specialist is your sole responsibility and is a decision that should be undertaken with care. For example, you may consider checking credentials with the appropriate medical boards. In addition, you can obtain names of other specialists (not listed within the Locator) by contacting a medical society.

The Companies disclaim any responsibility to update or otherwise maintain the information contained in the Locator. Furthermore, because the Companies: (i) compile such information from independent sources over whom the Companies have no control, and (ii) may experience reporting and processing errors or delays with respect to the information obtained through this website including, without limitation, the implied warranties of merchantability and fitness for any particular purpose. The material included in this website is for informational purposes only.

Inclusion of a specialist is not and does not imply referral, endorsement, or recommendation by the Companies, nor does the omission of any individual indicate disapproval by the Companies.

The Companies shall not be liable to you or others for any decisions made or action taken by you or others in reliance on the information obtained from this website.