Self-injection with the XOLAIR prefilled syringe

When starting treatment XOLAIR should be given by your healthcare provider in a healthcare setting. After you've established your XOLAIR treatment in a doctor's office or infusion center, your doctor will determine if you or a caregiver may inject XOLAIR.

If your doctor decides that you or a caregiver may be able to give your own XOLAIR prefilled syringe injections, you should receive training on the right way to prepare and inject XOLAIR. Do not try to inject your XOLAIR prefilled syringe until you have been shown the right way to give XOLAIR injections by your doctor. For children 12 years of age and older, the XOLAIR prefilled syringe may be self-injected under adult supervision. For children 6 to 11 years of age, the XOLAIR prefilled syringe should be injected by a caregiver.

You can find helpful information here on this site. As always, your healthcare team is your best resource.

You can schedule a virtual session with certified personnel by calling 1-866-878-0493. 

Watch this supplemental step-by-step video guide on how to properly prepare, inject, store, and dispose of the XOLAIR prefilled syringe(s).


How to Store XOLAIR

Your XOLAIR prefilled syringe will be shipped to you from the pharmacy under refrigerated conditions. It is important to store it as directed below.

Disposing of XOLAIR Syringes Safely

  • Throw away (dispose of) your used XOLAIR prefilled syringes in an FDA cleared sharps disposal container right away after use
  • The XOLAIR prefilled syringe is a single-dose prefilled syringe and should not be used again
  • Do not throw away prefilled syringes in your household trash
  • Do not recap the needle

For more information about safe sharps disposal, and for specific information about sharps disposal in the state that you live in, go to the FDA’s website at:

*Sharps Container—a heavy-duty, leak-proof container with a sealable lid that is designated by the FDA as a biomedical waste receptacle, generally used for discarding objects that can be used to puncture skin.

You should reach out to your pharmacy for a sharps disposal container. All pharmacies have different processes. If you do not have a sharps disposal container, you may use a household container that can stand upright, made of heavy-duty, leak-resistant plastic with a tight-fitting, puncture-resistant lid. Make sure to properly label the container as hazardous waste.

Frequently Asked Questions

Can I travel with XOLAIR?

What happens if I forget to take my XOLAIR?

What should I do if the XOLAIR carton is damaged?

What should I do if the prefilled syringe itself is damaged or past its expiration date?

What should I do if the medicine inside the prefilled syringe does not look right?

How long should I wait to use the prefilled syringe after taking XOLAIR out of the refrigerator?

What happens if the prefilled syringe does not reach room temperature before I use it?


What if I leave the prefilled syringe out for too long?

What if I activate the prefilled syringe guard too early?

How do I dispose of my used prefilled syringes?

How old do you have to be to self-administer the prefilled syringe?

How do I store XOLAIR?

What if my skin has a mole or scar?

What if I need more than 1 injection?

What should I do if I have questions about self-injection?