Why XOLAIR (Omalizumab) for Allergic Asthma Treatment?

XOLAIR for Allergic Asthma

XOLAIR is a prescription medicine used to treat appropriate allergic asthma patients. XOLAIR is not a medicine you inhale, and it is not a corticosteroid. It is for injection, given under the skin every 2 or 4 weeks by a nurse or doctor who is prepared to manage anaphylaxis, which can be life-threatening. If you or a child you care for has been diagnosed with allergic asthma, your asthma specialist may prescribe XOLAIR. To be prescribed XOLAIR, you must:

  • Have moderate to severe persistent allergic asthma
  • Be an adult or child who is 6 years of age or older
  • Have asthma symptoms that are not controlled—even though you are still taking inhaled corticosteroids. (Inhaled corticosteroids is a prescription medicine, breathed in through an inhaler, for people with asthma; it is intended for long-term, daily use to help prevent symptoms such as swelling in the lungs.)

What is the most important information I should know about XOLAIR?

Severe allergic reaction. A severe allergic reaction called anaphylaxis can happen when you receive XOLAIR. The reaction can occur after the first dose, or after many doses. It may also occur right after a XOLAIR injection or days later. Anaphylaxis is a life-threatening condition and can lead to death. Go to the nearest emergency room right away if you have any of these symptoms of an allergic reaction:

  • wheezing, shortness of breath, cough, chest tightness, or trouble breathing
  • low blood pressure, dizziness, fainting, rapid or weak heartbeat, anxiety, or feeling of “impending doom”
  • flushing, itching, hives, or feeling warm
  • swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing

Your healthcare provider will monitor you closely for symptoms of an allergic reaction while you are receiving XOLAIR and for a period of time after your injection. Your healthcare provider should talk to you about getting medical treatment if you have symptoms of an allergic reaction after leaving the healthcare provider’s office or treatment center.

XOLAIR is not used to treat other allergic conditions, acute bronchospasm (an asthma attack) or status asthmaticus (a severe asthma attack requiring immediate medical attention).

Additional XOLAIR Information

  • XOLAIR is the only FDA-approved biologic drug specifically designed to treat allergic asthma
  • More than 200,000 patients 12 years of age and older have been treated with XOLAIR (based on U.S. data)
    • This number refers to appropriate allergic asthma patients 12 years of age and older treated from June 2003 until July 2016
    • As of July 2016, XOLAIR has also been approved to treat appropriate allergic asthma patients 6 to less than 12 years old

If you think you may have allergic asthma, an asthma specialist can help with diagnosing and treatment options. Asthma specialists include either an allergist (specializes in diseases of the immune system, including allergic diseases and asthma) or a pulmonologist (specializes in diseases of the lungs and breathing, including asthma).