XOLAIR for Chronic Hives With No Known Cause (Also Known as
Chronic Idiopathic Urticaria or CIU)

XOLAIR is a once-monthly injectable prescription medicine, given under the skin by a nurse or doctor, that treats CIU in patients 12 years of age and older who are not controlled by H1 antihistamines. H1 antihistamines are a type of medicine used to treat allergic reactions such as hay fever, hives, and insect bites and stings. XOLAIR is not used to treat other forms of urticaria. Read the full Medication Guide to learn more.

What Is the Most Important Information I Should Know About XOLAIR?

Severe allergic reaction. A severe allergic reaction called anaphylaxis can happen when you receive XOLAIR. The reaction can occur after the first dose, or after many doses. It may also occur right after a XOLAIR injection or days later. Anaphylaxis is a life-threatening condition and can lead to death. Go to the nearest emergency room right away if you have any of these symptoms of an allergic reaction:

  • wheezing, shortness of breath, cough, chest tightness, or trouble breathing
  • low blood pressure, dizziness, fainting, rapid or weak heartbeat, anxiety, or feeling of "impending doom"
  • flushing, itching, hives, or feeling warm
  • swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing

Your healthcare provider will monitor you closely for symptoms of an allergic reaction while you are receiving XOLAIR and for a period of time after your injection. Your healthcare provider should talk to you about getting medical treatment if you have symptoms of an allergic reaction after leaving the healthcare provider’s office or treatment center.

Talk to you allergist about XOLAIR (Omalizumab) Chronic Idiopathic Urticaria (CIU) Treatment

Talk to Your Doctor About CIU and XOLAIR

Whether you’ve been diagnosed with CIU and want to discuss treatment options or not yet diagnosed and want to know if your hive condition is CIU, these discussion guides can help start the conversation between you and your specialist.

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Chronic Idiopathic Urticaria (CIU) Treatment Patient Stories
Chronic Idiopathic Urticaria (CIU) Treatment Patient Stories

Patient Stories

Watch the stories of people like you living with CIU. Learn more about their journey from diagnosis to finding an appropriate treatment option, as well as support.