XOLAIR for Chronic Hives With No Known Cause (Also Known as
Chronic Idiopathic Urticaria or CIU)
XOLAIR is a once-monthly injectable prescription medicine, given under the skin by a nurse or doctor, that treats CIU in patients 12 years of age and older who are not controlled by H1 antihistamines. H1 antihistamines are a type of medicine used to treat allergic reactions such as hay fever, hives, and insect bites and stings. XOLAIR is not used to treat other forms of urticaria. Read the full Medication Guide to learn more.
What Is the Most Important Information I Should Know About XOLAIR?
Severe allergic reaction. A severe allergic reaction called
anaphylaxis can happen when you receive XOLAIR. The reaction can occur
after the first dose, or after many doses. It may also occur right
after a XOLAIR injection or days later. Anaphylaxis is a
life-threatening condition and can lead to death. Go to the nearest
emergency room right away if you have any of these symptoms of an
allergic reaction:
- wheezing, shortness of breath, cough, chest tightness, or trouble breathing
- low blood pressure, dizziness, fainting, rapid or weak heartbeat, anxiety, or feeling of "impending doom"
- flushing, itching, hives, or feeling warm
- swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing
Your healthcare provider will monitor you
closely for symptoms of an allergic reaction while you are receiving
XOLAIR and for a period of time after your injection. Your healthcare
provider should talk to you about getting medical treatment if you
have symptoms of an allergic reaction after leaving the healthcare
provider’s office or treatment center.

Talk to Your Doctor About CIU and XOLAIR
Whether you’ve been diagnosed with CIU and want to discuss treatment options or not yet diagnosed and want to know if your hive condition is CIU, these discussion guides can help start the conversation between you and your specialist.

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Patient Stories
Watch the stories of people like you living
with CIU. Learn more about their journey from diagnosis to finding an
appropriate treatment option, as well as support.